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Regulatory landscape fusion in rhabdomyosarcoma through interactions between the PAX3 promoter and FOXO1 regulatory elements

BACKGROUND: The organisation of vertebrate genomes into topologically associating domains (TADs) is believed to facilitate the regulation of the genes located within them. A remaining question is whether TAD organisation is achieved through the interactions of the regulatory elements within them or...

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Detalles Bibliográficos
Autores principales: Vicente-García, Cristina, Villarejo-Balcells, Barbara, Irastorza-Azcárate, Ibai, Naranjo, Silvia, Acemel, Rafael D., Tena, Juan J., Rigby, Peter W. J., Devos, Damien P., Gómez-Skarmeta, Jose L., Carvajal, Jaime J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470208/
https://www.ncbi.nlm.nih.gov/pubmed/28615069
http://dx.doi.org/10.1186/s13059-017-1225-z