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Activation of Lineage Regulators and Transposable Elements across a Pluripotent Spectrum

Embryonic stem cells (ESCs) are characterized by the pluripotent capacity to generate all embryonic lineages. Here, we show that ESCs can occupy a spectrum of distinct transcriptional and epigenetic states in response to varied extrinsic conditions. This spectrum broadly corresponds to a development...

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Detalles Bibliográficos
Autores principales: Hackett, Jamie A., Kobayashi, Toshihiro, Dietmann, Sabine, Surani, M. Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470235/
https://www.ncbi.nlm.nih.gov/pubmed/28591649
http://dx.doi.org/10.1016/j.stemcr.2017.05.014