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Activation of Lineage Regulators and Transposable Elements across a Pluripotent Spectrum
Embryonic stem cells (ESCs) are characterized by the pluripotent capacity to generate all embryonic lineages. Here, we show that ESCs can occupy a spectrum of distinct transcriptional and epigenetic states in response to varied extrinsic conditions. This spectrum broadly corresponds to a development...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470235/ https://www.ncbi.nlm.nih.gov/pubmed/28591649 http://dx.doi.org/10.1016/j.stemcr.2017.05.014 |