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The effect of Astragalus polysaccharides on attenuation of diabetic cardiomyopathy through inhibiting the extrinsic and intrinsic apoptotic pathways in high glucose -stimulated H9C2 cells

BACKGROUND: Apoptosis plays a critical role in the progression of diabetic cardiomyopathy (DC). Astragalus polysaccharides (APS), an extract of astragalus membranaceus (AM), is an effective cardioprotectant. Currently, little is known about the detailed mechanisms underlying cardioprotective effects...

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Detalles Bibliográficos
Autores principales: Sun, Shuqin, Yang, Shuo, Dai, Min, Jia, Xiujuan, Wang, Qiyan, Zhang, Zheng, Mao, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470251/
https://www.ncbi.nlm.nih.gov/pubmed/28610566
http://dx.doi.org/10.1186/s12906-017-1828-7