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Stem cell models of Alzheimer’s disease: progress and challenges

A major challenge to our understanding of the molecular mechanisms of Alzheimer’s disease (AD) has been the lack of physiologically relevant in vitro models which capture the precise patient genome, in the cell type of interest, with physiological expression levels of the gene(s) of interest. Induce...

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Detalles Bibliográficos
Autores principales: Arber, Charles, Lovejoy, Christopher, Wray, Selina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470327/
https://www.ncbi.nlm.nih.gov/pubmed/28610595
http://dx.doi.org/10.1186/s13195-017-0268-4