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Stem cell models of Alzheimer’s disease: progress and challenges
A major challenge to our understanding of the molecular mechanisms of Alzheimer’s disease (AD) has been the lack of physiologically relevant in vitro models which capture the precise patient genome, in the cell type of interest, with physiological expression levels of the gene(s) of interest. Induce...
Autores principales: | Arber, Charles, Lovejoy, Christopher, Wray, Selina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470327/ https://www.ncbi.nlm.nih.gov/pubmed/28610595 http://dx.doi.org/10.1186/s13195-017-0268-4 |
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