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Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells

Pluripotent stem cells have been proposed as an unlimited source of pancreatic β cells for studying and treating diabetes. However, the long, multi-step differentiation protocols used to generate functional β cells inevitably exhibit considerable variability, particularly when applied to pluripotent...

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Detalles Bibliográficos
Autores principales: Trott, Jamie, Tan, Ee Kim, Ong, Sheena, Titmarsh, Drew M., Denil, Simon L.I.J., Giam, Maybelline, Wong, Cheng Kit, Wang, Jiaxu, Shboul, Mohammad, Eio, Michelle, Cooper-White, Justin, Cool, Simon M., Rancati, Giulia, Stanton, Lawrence W., Reversade, Bruno, Dunn, N. Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470345/
https://www.ncbi.nlm.nih.gov/pubmed/28591650
http://dx.doi.org/10.1016/j.stemcr.2017.05.019