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Rapid decrease of circulating tumor DNA predicted the treatment effect of nivolumab in a lung cancer patient within only 5 days

A 77-year-old Japanese man presented to our hospital with a 1-month history of low back pain and was diagnosed as having stage IV EGFR mutation-positive lung adenocarcinoma. After treatment with EGFR tyrosine kinase inhibitor and cytotoxic chemotherapy, nivolumab was started as fourth-line therapy....

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Detalles Bibliográficos
Autores principales: Iijima, Yuki, Hirotsu, Yosuke, Amemiya, Kenji, Higashi, Seishi, Miyashita, Yoshihiro, Omata, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470530/
https://www.ncbi.nlm.nih.gov/pubmed/28649487
http://dx.doi.org/10.1016/j.rmcr.2017.05.015