Higher oxidative stress in skeletal muscle of McArdle disease patients

McArdle disease (MCD) is an autosomal recessive condition resulting from skeletal muscle glycogen phosphorylase deficiency. The resultant block in glycogenolysis leads to an increased flux through the xanthine oxidase pathway (myogenic hyperuricemia) and could lead to an increase in oxidative stress...

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Detalles Bibliográficos
Autores principales: Kaczor, Jan J., Robertshaw, Holly A., Tarnopolsky, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470535/
https://www.ncbi.nlm.nih.gov/pubmed/28649515
http://dx.doi.org/10.1016/j.ymgmr.2017.05.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470535/
https://www.ncbi.nlm.nih.gov/pubmed/28649515
http://dx.doi.org/10.1016/j.ymgmr.2017.05.009

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