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Global Analysis of Cellular Protein Flux Quantifies the Selectivity of Basal Autophagy

In eukaryotic cells, macroautophagy is a catabolic pathway implicated in the degradation of long-lived proteins and damaged organelles. Although it has been demonstrated that macroautophagy can selectively degrade specific targets, its contribution to the basal turnover of cellular proteins has not...

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Detalles Bibliográficos
Autores principales: Zhang, Tian, Shen, Shichen, Qu, Jun, Ghaemmaghami, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470642/
https://www.ncbi.nlm.nih.gov/pubmed/26947064
http://dx.doi.org/10.1016/j.celrep.2016.02.040