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Intestinal organoids model human responses to infection by commensal and Shiga toxin producing Escherichia coli

Infection with Shiga toxin (Stx) producing Escherichia coli O157:H7 can cause the potentially fatal complication hemolytic uremic syndrome, and currently only supportive therapy is available. Lack of suitable animal models has hindered study of this disease. Induced human intestinal organoids (iHIOs...

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Detalles Bibliográficos
Autores principales: Karve, Sayali S., Pradhan, Suman, Ward, Doyle V., Weiss, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470682/
https://www.ncbi.nlm.nih.gov/pubmed/28614372
http://dx.doi.org/10.1371/journal.pone.0178966