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Intestinal organoids model human responses to infection by commensal and Shiga toxin producing Escherichia coli
Infection with Shiga toxin (Stx) producing Escherichia coli O157:H7 can cause the potentially fatal complication hemolytic uremic syndrome, and currently only supportive therapy is available. Lack of suitable animal models has hindered study of this disease. Induced human intestinal organoids (iHIOs...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470682/ https://www.ncbi.nlm.nih.gov/pubmed/28614372 http://dx.doi.org/10.1371/journal.pone.0178966 |