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Accurate prediction of functional effects for variants by combining gradient tree boosting with optimal neighborhood properties
Single amino acid variations (SAVs) potentially alter biological functions, including causing diseases or natural differences between individuals. Identifying the relationship between a SAV and certain disease provides the starting point for understanding the underlying mechanisms of specific associ...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470696/ https://www.ncbi.nlm.nih.gov/pubmed/28614374 http://dx.doi.org/10.1371/journal.pone.0179314 |