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Hypoxia Inducible Factor (HIF) transcription factor family expansion, diversification, divergence and selection in eukaryotes

Hypoxia inducible factor (HIF) transcription factors are crucial for regulating a variety of cellular activities in response to oxygen stress (hypoxia). In this study, we determine the evolutionary history of HIF genes and their associated transactivation domains, as well as perform selection and fu...

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Detalles Bibliográficos
Autores principales: Graham, Allie M., Presnell, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470732/
https://www.ncbi.nlm.nih.gov/pubmed/28614393
http://dx.doi.org/10.1371/journal.pone.0179545