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Modified-Release and Conventional Glucocorticoids and Diurnal Androgen Excretion in Congenital Adrenal Hyperplasia

CONTEXT: The classic androgen synthesis pathway proceeds via dehydroepiandrosterone, androstenedione, and testosterone to 5α-dihydrotestosterone. However, 5α-dihydrotestosterone synthesis can also be achieved by an alternative pathway originating from 17α-hydroxyprogesterone (17OHP), which accumulat...

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Detalles Bibliográficos
Autores principales: Jones, Christopher M., Mallappa, Ashwini, Reisch, Nicole, Nikolaou, Nikolaos, Krone, Nils, Hughes, Beverly A., O’Neil, Donna M., Whitaker, Martin J., Tomlinson, Jeremy W., Storbeck, Karl-Heinz, Merke, Deborah P., Ross, Richard J., Arlt, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470768/
https://www.ncbi.nlm.nih.gov/pubmed/27845856
http://dx.doi.org/10.1210/jc.2016-2855