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Long noncoding RNA PCAT-14 induces proliferation and invasion by hepatocellular carcinoma cells by inducing methylation of miR-372

Long non-coding RNAs (lncRNAs) regulate oncogenesis by inducing methylation of CpG islands to silence target genes. Here we show that the lncRNA PCAT-14 is overexpressed in patients with hepatocellular carcinoma (HCC), and is associated with a poor prognosis after surgery. Our results demonstrate th...

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Detalles Bibliográficos
Autores principales: Wang, Yawei, Hu, Ye, Wu, Gang, Yang, Ye, Tang, Yanqing, Zhang, Wanchuan, Wang, Kaiyu, Liu, Yu, Wang, Xin, Li, Tiemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470980/
https://www.ncbi.nlm.nih.gov/pubmed/28415780
http://dx.doi.org/10.18632/oncotarget.16260