Thymoquinone exerts potent growth-suppressive activity on leukemia through DNA hypermethylation reversal in leukemia cells

Thymoquinone (TQ), a bioactive constituent of the volatile oil of Monarda fistulosa and Nigella sativa, possesses cancer-specific growth inhibitory effects, but the underlying molecular mechanisms remain largely elusive. We propose that TQ curbs cancer cell growth through dysfunction of DNA methyltr...

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Detalles Bibliográficos
Autores principales: Pang, Jiuxia, Shen, Na, Yan, Fei, Zhao, Na, Dou, Liping, Wu, Lai-Chu, Seiler, Christopher L., Yu, Li, Yang, Ke, Bachanova, Veronika, Weaver, Eric, Tretyakova, Natalia Y., Liu, Shujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470982/
https://www.ncbi.nlm.nih.gov/pubmed/28415607
http://dx.doi.org/10.18632/oncotarget.16431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470982/
https://www.ncbi.nlm.nih.gov/pubmed/28415607
http://dx.doi.org/10.18632/oncotarget.16431

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