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Thymoquinone exerts potent growth-suppressive activity on leukemia through DNA hypermethylation reversal in leukemia cells
Thymoquinone (TQ), a bioactive constituent of the volatile oil of Monarda fistulosa and Nigella sativa, possesses cancer-specific growth inhibitory effects, but the underlying molecular mechanisms remain largely elusive. We propose that TQ curbs cancer cell growth through dysfunction of DNA methyltr...
Autores principales: | Pang, Jiuxia, Shen, Na, Yan, Fei, Zhao, Na, Dou, Liping, Wu, Lai-Chu, Seiler, Christopher L., Yu, Li, Yang, Ke, Bachanova, Veronika, Weaver, Eric, Tretyakova, Natalia Y., Liu, Shujun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470982/ https://www.ncbi.nlm.nih.gov/pubmed/28415607 http://dx.doi.org/10.18632/oncotarget.16431 |
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