Usefulness of the MRP2 promoter to overcome the chemoresistance of gastrointestinal and liver tumors by enhancing the expression of the drug transporter OATP1B1

Tumor response to chemotherapy is often limited by drug export through ABC proteins. To overcome this problem, here we have investigated the usefulness of inducing the expression of the multidrug uptake transporter OATP1B1 under the control of the MRP2 promoter (MRP2pr). Human hepatoma cells (Alexan...

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Detalles Bibliográficos
Autores principales: Herraez, Elisa, Sanchez-Vicente, Laura, Macias, Rocio I.R., Briz, Oscar, Jose, J.G. Marin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470996/
https://www.ncbi.nlm.nih.gov/pubmed/28423714
http://dx.doi.org/10.18632/oncotarget.16119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470996/
https://www.ncbi.nlm.nih.gov/pubmed/28423714
http://dx.doi.org/10.18632/oncotarget.16119

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