A functional variant at the miRNA binding site in HMGB1 gene is associated with risk of oral squamous cell carcinoma

Oral squamous cell carcinoma (OSCC) is a common malignancy that has been causally associated with both hereditary and acquired factors. The high mobility group box 1 (HMGB1) gene plays an important role as a DNA chaperone to help maintain nuclear homeostasis. Altered expression of HMGB1 has been imp...

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Detalles Bibliográficos
Autores principales: Lin, Chiao-Wen, Chou, Ying-Erh, Yeh, Chia-Ming, Yang, Shun-Fa, Chuang, Chun-Yi, Liu, Yu-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470997/
https://www.ncbi.nlm.nih.gov/pubmed/28423715
http://dx.doi.org/10.18632/oncotarget.16120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470997/
https://www.ncbi.nlm.nih.gov/pubmed/28423715
http://dx.doi.org/10.18632/oncotarget.16120

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