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MicroRNA-100 suppresses human osteosarcoma cell proliferation and chemo-resistance via ZNRF2

Osteosarcoma (OS) is a prevalent cancer worldwide. MicroRNAs (miRNAs) play critical roles in the growth, invasion and carcinogenesis of OS, whereas the underlying mechanisms remain ill-defined. Here, we addressed these questions. We detected significantly higher levels of ZNRF2, a ubiquitin ligase o...

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Detalles Bibliográficos
Autores principales: Xiao, Qiang, Yang, Yu, An, Qing, Qi, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471002/
https://www.ncbi.nlm.nih.gov/pubmed/28416774
http://dx.doi.org/10.18632/oncotarget.16149