In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro (18)F-FDG PET/CT

PURPOSE: Hypoxia-inducible factor 1α (HIF-1α) and glucose transporter-1 (GLUT-1) are two important hypoxic markers associated with the radioresistance of cancers including laryngeal carcinoma. We evaluated whether the simultaneous inhibition of GLUT-1 and HIF-1α expression improved the radiosensitiv...

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Detalles Bibliográficos
Autores principales: Shen, Li-Fang, Zhao, Xin, Zhou, Shui-Hong, Lu, Zhong-Jie, Zhao, Kui, Fan, Jun, Zhou, Min-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471005/
https://www.ncbi.nlm.nih.gov/pubmed/28410229
http://dx.doi.org/10.18632/oncotarget.16671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471005/
https://www.ncbi.nlm.nih.gov/pubmed/28410229
http://dx.doi.org/10.18632/oncotarget.16671

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