Cargando…

In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro (18)F-FDG PET/CT

PURPOSE: Hypoxia-inducible factor 1α (HIF-1α) and glucose transporter-1 (GLUT-1) are two important hypoxic markers associated with the radioresistance of cancers including laryngeal carcinoma. We evaluated whether the simultaneous inhibition of GLUT-1 and HIF-1α expression improved the radiosensitiv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shen, Li-Fang, Zhao, Xin, Zhou, Shui-Hong, Lu, Zhong-Jie, Zhao, Kui, Fan, Jun, Zhou, Min-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471005/ https://www.ncbi.nlm.nih.gov/pubmed/28410229 http://dx.doi.org/10.18632/oncotarget.16671

Ejemplares similares

Effect of Antisense Oligodeoxynucleotides Glucose Transporter-1 on Enhancement of Radiosensitivity of Laryngeal Carcinoma
por: Yan, Sen-Xiang, et al.
Publicado: (2013)

Effect of Glut‐1 and HIF‐1α double knockout by CRISPR/CAS9 on radiosensitivity in laryngeal carcinoma via the PI3K/Akt/mTOR pathway
por: Bao, Yang‐Yang, et al.
Publicado: (2022)

Antisense oligodeoxynucleotides targeting ATM strengthen apoptosis of laryngeal squamous cell carcinoma grown in nude mice
por: Feng, Jun, et al.
Publicado: (2011)

Co-Inhibition of GLUT-1 Expression and the PI3K/Akt Signaling Pathway to Enhance the Radiosensitivity of Laryngeal Carcinoma Xenografts In Vivo
por: Luo, Xing-Mei, et al.
Publicado: (2015)

GLUT-1 siRNA Enhances Radiosensitization Of Laryngeal Cancer Stem Cells Via Enhanced DNA Damage, Cell Cycle Redistribution, And Promotion Of Apoptosis In Vitro And In Vivo
por: Zhong, Jiang-Tao, et al.
Publicado: (2019)

Photomodulating RNA cleavage using photolabile circular antisense oligodeoxynucleotides
por: Tang, XinJing, et al.
Publicado: (2010)

Anorectal leiomyoma with GLUT1 overexpression mimicking malignancy on FDG-PET/CT
por: Teraishi, Fuminori, et al.
Publicado: (2022)

HIF-1 and tumour radiosensitivity
por: Moeller, B J, et al.
Publicado: (2006)

The use of synthetic polymers for delivery of therapeutic antisense oligodeoxynucleotides
por: Chirila, Traian V, et al.
Publicado: (2002)

Antisense oligodeoxynucleotide against human telomerase reverse transcriptase inhibits the proliferation of Eca-109 esophageal carcinoma cells
por: FAN, XIANG-KUI, et al.
Publicado: (2014)

Significance of (18) F-FDG PET and immunohistochemical GLUT-1 expression for cardiac myxoma
por: Okazaki, Yukio, et al.
Publicado: (2014)

The role of Glut-1 and H(+)/K(+)-ATPase expression in hyperplasia of mice laryngeal epithelium induced by pepsin
por: Ao, Yin-Jie, et al.
Publicado: (2022)

Effect of Antisense TGF-β1 Oligodeoxynucleotides in Streptozotocin-Induced Diabetic Rat Kidney
por: Jeong, Hyo Soon, et al.
Publicado: (2004)

Expression of Glut-1, HIF-1α, PI3K and p-Akt in a case of ceruminous adenoma
por: Shen, Wan-Qin, et al.
Publicado: (2012)

GLUT1, GLUT3 Expression and 18FDG-PET/CT in Human Malignant Melanoma: What Relationship Exists? New Insights and Perspectives
por: Cazzato, Gerardo, et al.
Publicado: (2021)

Fundamental differences in the equilibrium considerations for siRNA and antisense oligodeoxynucleotide design
por: Lu, Zhi John, et al.
Publicado: (2008)

Correlation of Glut-1 and Glut-3 expression with F-18 FDG uptake in pulmonary inflammatory lesions
por: Wang, Zhen Guang, et al.
Publicado: (2016)

Antisense Oligodeoxynucleotide Inhibition as an Alternative and Convenient Method for Gene Function Analysis in Pollen Tubes
por: Liao, Fanglei, et al.
Publicado: (2013)

Construction of a GLUT-1 and HIF-1α gene knockout cell model in HEp-2 cells using the CRISPR/Cas9 technique
por: Lu, Zhong-Jie, et al.
Publicado: (2019)

Growth factor-dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotides
Publicado: (1992)

Laryngeal Tuberculosis Mimicking Laryngeal Carcinoma on (18)F-FDG PET/CT Imaging
por: Cengiz, Arzu, et al.
Publicado: (2018)

Targeted Inhibition of HK-II Reversed the Warburg Effect to Improve the Radiosensitivity of Laryngeal Carcinoma
por: Chen, Xiao-Hong, et al.
Publicado: (2021)

Effect of GLUT1 Inhibition and Autophagy Modulation on the Growth and Migration of Laryngeal Carcinoma Stem Cells Under Hypoxic and Low-Glucose Conditions
por: Chen, Xiao-Hong, et al.
Publicado: (2021)

Prognostic Value of FDG PET Imaging in Patients with Laryngeal Cancer
por: Kitajima, Kazuhiro, et al.
Publicado: (2014)

Leukemia treatment in severe combined immunodeficiency mice by antisense oligodeoxynucleotides targeting cooperating oncogenes
Publicado: (1995)

Relationships between expression of glucose transporter protein-1 and hypoxia inducible factor-1α, prognosis and (18)F-FDG uptake in laryngeal and hypopharyngeal carcinomas
por: Shen, Li-Fang, et al.
Publicado: (2020)

Inhibition of GLUT-1 expression and the PI3K/Akt pathway to enhance the chemosensitivity of laryngeal carcinoma cells in vitro
por: Jiang, Tao, et al.
Publicado: (2018)

Metabolic Heterogeneity of Cancer Cells: An Interplay between HIF-1, GLUTs, and AMPK
por: Moldogazieva, Nurbubu T., et al.
Publicado: (2020)

TNF induces glycolytic shift in fibroblast like synoviocytes via GLUT1 and HIF1A
por: Koedderitzsch, Kathrin, et al.
Publicado: (2021)

The decoy oligodeoxynucleotide against HIF-1α and STAT5 ameliorates atopic dermatitis-like mouse model
por: Gwon, Mi-Gyeong, et al.
Publicado: (2023)

Prognostic impact of the combination of HIF‑1α and GLUT1 in patients with oesophageal squamous cell carcinoma
por: Yi, Hanjie, et al.
Publicado: (2023)

Activation of Hif1α by the Prolylhydroxylase Inhibitor Dimethyoxalyglycine Decreases Radiosensitivity
por: Ayrapetov, Marina K., et al.
Publicado: (2011)

Expression of NR1 subunit of NMDA receptor and PSD-93/95 in rat hippocampus affected by NR1/NR2 antisense oligodeoxynucleotide
por: Vrajová, Monika, et al.
Publicado: (2010)

2-Methoxyestradiol enhances radiosensitivity in radioresistant melanoma MDA-MB-435R cells by regulating glycolysis via HIF-1α/PDK1 axis
por: Zhao, Hong, et al.
Publicado: (2017)

Oxygen metabolism in oral cancer: HIF and GLUTs (Review)
por: PEREIRA, KARUZA MARIA ALVES, et al.
Publicado: (2013)

Antisense oligodeoxynucleotides against dynamin-related protein 1 reduce remifentanil-induced hyperalgesia by modulating spinal N-methyl-D-aspartate receptor expression in rats
por: Zhou, Songyi, et al.
Publicado: (2023)

Translation of stable hepadnaviral mRNA cleavage fragments induced by the action of phosphorothioate-modified antisense oligodeoxynucleotides
por: Hasselblatt, Peter, et al.
Publicado: (2005)

Palatine Tonsillar Metastasis of Small-Cell Neuroendocrine Carcinoma from the Lung Detected by FDG-PET/CT After Tonsillectomy: A Case Report
por: Chen, Xiao-Hong, et al.
Publicado: (2013)

Inhibition of lung adenocarcinoma cells by insulin-like growth factor-I receptor and Kirsten rat sarcoma mutations: A mutation analysis with antisense oligodeoxynucleotide
por: Li, Shaoming, et al.
Publicado: (2015)

Tyrosine Kinase Inhibitors Reduce Glucose Uptake by Binding to an Exofacial Site on hGLUT‐1: Influence on (18)F‐FDG PET Uptake
por: Damaraju, Vijaya L., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_p33aa0eqkf760c7q6h541k30vb