Factors affecting the loss of MED12-mutated leiomyoma cells during in vitro growth

Uterine leiomyomas (UL) are the most prevalent symptomatic human tumors at all and somatic mutations of the gene encoding mediator subcomplex 12 (MED12) constitute the most frequent driver mutations in UL. Recently, a rapid loss of mutated cells during in vitro growth of UL-derived cell cultures was...

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Detalles Bibliográficos
Autores principales: Bloch, Jeannine, Holzmann, Carsten, Koczan, Dirk, Helmke, Burkhard Maria, Bullerdiek, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471009/
https://www.ncbi.nlm.nih.gov/pubmed/28410233
http://dx.doi.org/10.18632/oncotarget.16711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471009/
https://www.ncbi.nlm.nih.gov/pubmed/28410233
http://dx.doi.org/10.18632/oncotarget.16711

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