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Loss-of-function myostatin mutation increases insulin sensitivity and browning of white fat in Meishan pigs

Myostatin-deficient mice showed a remarkable hypertrophy of skeletal muscle, with a decreased fat mass and enhanced insulin sensitivity. Currently, it is unclear if the inhibition of myostatin could be used as an approach to treat human obesity and insulin resistance. In this study, we investigated...

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Detalles Bibliográficos
Autores principales: Cai, Chunbo, Qian, Lili, Jiang, Shengwang, Sun, Youde, Wang, Qingqing, Ma, Dezun, Xiao, Gaojun, Li, Biao, Xie, Shanshan, Gao, Ting, Chen, Yaoxing, Liu, Jie, An, Xiaorong, Cui, Wentao, Li, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471021/
https://www.ncbi.nlm.nih.gov/pubmed/28432282
http://dx.doi.org/10.18632/oncotarget.16822