Gαi3 nuclear translocation causes irradiation resistance in human glioma cells

We have previously shown that Gαi3 is elevated in human glioma, mediating Akt activation and cancer cell proliferation. Here, we imply that Gαi3 could also be important for irradiation resistance. In A172 human glioma cells, Gαi3 knockdown (by targeted shRNAs) or dominant-negative mutation significa...

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Detalles Bibliográficos
Autores principales: Cai, Shang, Li, Ya, Bai, Jin-Yu, Zhang, Zhi-Qing, Wang, Yin, Qiao, Yin-Biao, Zhou, Xiao-Zhong, Yang, Bo, Tian, Ye, Cao, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471034/
https://www.ncbi.nlm.nih.gov/pubmed/28456783
http://dx.doi.org/10.18632/oncotarget.17043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471034/
https://www.ncbi.nlm.nih.gov/pubmed/28456783
http://dx.doi.org/10.18632/oncotarget.17043

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