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Clinical validation of prospective liquid biopsy monitoring in patients with wild-type RAS metastatic colorectal cancer treated with FOLFIRI-cetuximab

Cancer genomics and translational medicine rely on the molecular profiling of patient's tumor obtained during surgery or biopsy. Alternatively, blood is a less invasive source of tumor DNA shed, amongst other ways, as cell-free DNA (cfDNA). Highly-sensitive assays capable to detect cancer genet...

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Detalles Bibliográficos
Autores principales: Toledo, Rodrigo A., Cubillo, Antonio, Vega, Estela, Garralda, Elena, Alvarez, Rafael, de la Varga, Lisardo U., Pascual, Jesús R., Sánchez, Gema, Sarno, Francesca, Prieto, Susana H., Perea, Sofía, Lopéz-Casas, Pedro P., López-Ríos, Fernando, Hidalgo, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471055/
https://www.ncbi.nlm.nih.gov/pubmed/27852040
http://dx.doi.org/10.18632/oncotarget.13311