Successful reduction of high-sustained anti-idursulfase antibody titers by immune modulation therapy in a patient with severe mucopolysaccharidosis type II

We report on a 6 year old boy with severe MPS II undergoing immune modulation therapy due to high IgG antibody titers to IV idursulfase and no significant decline in urinary GAG levels since initiating enzyme replacement therapy. He has complete deficiency of iduronate-2-sulfatase activity due to a...

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Detalles Bibliográficos
Autores principales: Kim, Katherine H., Messinger, Yoav H., Burton, Barbara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471157/
https://www.ncbi.nlm.nih.gov/pubmed/28649520
http://dx.doi.org/10.1016/j.ymgmr.2014.11.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471157/
https://www.ncbi.nlm.nih.gov/pubmed/28649520
http://dx.doi.org/10.1016/j.ymgmr.2014.11.007

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