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Bone morphogenetic protein 4 promotes the survival and preserves the structure of flow-sorted Bhlhb5+ cochlear spiral ganglion neurons in vitro

SGNs are the primary auditory neurons, and damage or loss of SGNs leads to sensorineural hearing loss. BMP4 is a growth factor that belongs to the TGF-β superfamily and has been shown to play a key role during development, but little is known about its effect on postnatal cochlear SGNs in mice. In t...

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Detalles Bibliográficos
Autores principales: Waqas, Muhammad, Sun, Shan, Xuan, Chuanyin, Fang, Qiaojun, Zhang, Xiaoli, Islam, Irum-us, Qi, Jieyu, Zhang, Shasha, Gao, Xia, Tang, Mingliang, Shi, Haibo, Li, Huawei, Chai, Renjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471210/
https://www.ncbi.nlm.nih.gov/pubmed/28615657
http://dx.doi.org/10.1038/s41598-017-03810-w