Improving the detection of pathways in genome-wide association studies by combined effects of SNPs from Linkage Disequilibrium blocks

Genome-wide association studies (GWAS) have successfully identified single variants associated with diseases. To increase the power of GWAS, gene-based and pathway-based tests are commonly employed to detect more risk factors. However, the gene- and pathway-based association tests may be biased towa...

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Detalles Bibliográficos
Autores principales: Zhao, Huiying, Nyholt, Dale R., Yang, Yuanhao, Wang, Jihua, Yang, Yuedong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471232/
https://www.ncbi.nlm.nih.gov/pubmed/28615668
http://dx.doi.org/10.1038/s41598-017-03826-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471232/
https://www.ncbi.nlm.nih.gov/pubmed/28615668
http://dx.doi.org/10.1038/s41598-017-03826-2

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