Cargando…
Neuronal P2X7 receptor-induced reactive oxygen species production contributes to nociceptive behavior in mice
ATP can activate a variety of pathways through P2 purinoreceptors, leading to neuroprotection and pathology in the CNS. Among all P2X receptors, the P2X7 receptor (P2X7R) is a well-defined therapeutic target for inflammatory and neuropathic pain. Activation of P2X7R can generate reactive oxygen spec...
Autores principales: | Munoz, Frances M., Gao, Ruby, Tian, Yuzhen, Henstenburg, Brian A., Barrett, James E., Hu, Huijuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471238/ https://www.ncbi.nlm.nih.gov/pubmed/28615626 http://dx.doi.org/10.1038/s41598-017-03813-7 |
Ejemplares similares
-
TNF-α Increases Production of Reactive Oxygen Species through Cdk5 Activation in Nociceptive Neurons
por: Sandoval, Rodrigo, et al.
Publicado: (2018) -
Activation of planarian TRPA1 by reactive oxygen species reveals a conserved mechanism for nociception
por: Arenas, Oscar M., et al.
Publicado: (2017) -
Gastric Cancer Vascularization and the Contribution of Reactive Oxygen Species
por: Biagioni, Alessio, et al.
Publicado: (2023) -
Atrial fibrillation in the elderly: the potential contribution of reactive oxygen species
por: Schillinger, Kurt J., et al.
Publicado: (2012) -
Contribution of Reactive Oxygen Species to Thymineless Death in Escherichia coli
por: Hong, Yuzhi, et al.
Publicado: (2017)