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Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock

BACKGROUND: Cystathionine-γ-lyase (CSE) was shown to have a regulatory role in glucose metabolism. Circulatory shock can induce metabolic stress, thereby leading to hyperglycemia and mitochondrial dysfunction. In vitro data suggest an effect of high glucose on CSE expression. Therefore, the aim of t...

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Detalles Bibliográficos
Autores principales: Merz, Tamara, Vogt, Josef A., Wachter, Ulrich, Calzia, Enrico, Szabo, Csaba, Wang, Rui, Radermacher, Peter, McCook, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471286/
https://www.ncbi.nlm.nih.gov/pubmed/28616781
http://dx.doi.org/10.1186/s40635-017-0140-7