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Docking Based 3D-QSAR Study of Tricyclic Guanidine Analogues of Batzelladine K As Anti-Malarial Agents

The Plasmodium falciparum Lactate Dehydrogenase enzyme (PfLDH) catalyzes inter-conversion of pyruvate to lactate during glycolysis producing the energy required for parasitic growth. The PfLDH has been studied as a potential molecular target for development of anti-malarial agents. In an attempt to...

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Detalles Bibliográficos
Autores principales: Ahmed, Nafees, Anwar, Sirajudheen, Thet Htar, Thet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471292/
https://www.ncbi.nlm.nih.gov/pubmed/28664157
http://dx.doi.org/10.3389/fchem.2017.00036