Cargando…

Activation of Transient Receptor Potential Vanilloid 4 Impairs the Dendritic Arborization of Newborn Neurons in the Hippocampal Dentate Gyrus through the AMPK and Akt Signaling Pathways

Neurite growth is an important process for the adult hippocampal neurogenesis which is regulated by a specific range of the intracellular free Ca(2+) concentration ([Ca(2+)](i)). Transient receptor potential vanilloid 4 (TRPV4) is a calcium-permeable channel and activation of it causes an increase i...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Yujing, Qi, Mengwen, Wang, Zhouqing, Wu, Chunfeng, Sun, Zhen, Li, Yingchun, Sha, Sha, Du, Yimei, Chen, Lei, Chen, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471311/
https://www.ncbi.nlm.nih.gov/pubmed/28663724
http://dx.doi.org/10.3389/fnmol.2017.00190