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Activation of Transient Receptor Potential Vanilloid 4 Impairs the Dendritic Arborization of Newborn Neurons in the Hippocampal Dentate Gyrus through the AMPK and Akt Signaling Pathways
Neurite growth is an important process for the adult hippocampal neurogenesis which is regulated by a specific range of the intracellular free Ca(2+) concentration ([Ca(2+)](i)). Transient receptor potential vanilloid 4 (TRPV4) is a calcium-permeable channel and activation of it causes an increase i...
Autores principales: | Tian, Yujing, Qi, Mengwen, Wang, Zhouqing, Wu, Chunfeng, Sun, Zhen, Li, Yingchun, Sha, Sha, Du, Yimei, Chen, Lei, Chen, Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471311/ https://www.ncbi.nlm.nih.gov/pubmed/28663724 http://dx.doi.org/10.3389/fnmol.2017.00190 |
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