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Geldanamycin Reduces Acute Respiratory Distress Syndrome and Promotes the Survival of Mice Infected with the Highly Virulent H5N1 Influenza Virus

Infections with lethal influenza viruses lead to acute lung injury (ALI) or acute respiratory distress syndrome (ARDS), which may be related to the activation of the host's immune system. Here, in our study, male C57BL/6 mice were infected with 10 LD(50) of the H5N1 influenza virus and treated...

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Detalles Bibliográficos
Autores principales: Wang, Chengmin, Liu, Pengpeng, Luo, Jing, Ding, Hua, Gao, Yan, Sun, Lei, Luo, Fubing, Liu, Xiaodong, He, Hongxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471324/
https://www.ncbi.nlm.nih.gov/pubmed/28664154
http://dx.doi.org/10.3389/fcimb.2017.00267