Fluconazole-Induced Ploidy Change in Cryptococcus neoformans Results from the Uncoupling of Cell Growth and Nuclear Division

Cryptococcus neoformans is a pathogenic yeast that causes lethal cryptococcal meningitis in immunocompromised patients. One of the challenges in treating cryptococcosis is the development of resistance to azole antifungals. Previous studies linked azole resistance to elevated numbers of copies of cr...

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Detalles Bibliográficos
Autores principales: Altamirano, Sophie, Fang, Diana, Simmons, Charles, Sridhar, Shreyas, Wu, Peipei, Sanyal, Kaustuv, Kozubowski, Lukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471349/
https://www.ncbi.nlm.nih.gov/pubmed/28630940
http://dx.doi.org/10.1128/mSphere.00205-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471349/
https://www.ncbi.nlm.nih.gov/pubmed/28630940
http://dx.doi.org/10.1128/mSphere.00205-17

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