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Fluconazole-Induced Ploidy Change in Cryptococcus neoformans Results from the Uncoupling of Cell Growth and Nuclear Division
Cryptococcus neoformans is a pathogenic yeast that causes lethal cryptococcal meningitis in immunocompromised patients. One of the challenges in treating cryptococcosis is the development of resistance to azole antifungals. Previous studies linked azole resistance to elevated numbers of copies of cr...
Autores principales: | Altamirano, Sophie, Fang, Diana, Simmons, Charles, Sridhar, Shreyas, Wu, Peipei, Sanyal, Kaustuv, Kozubowski, Lukasz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471349/ https://www.ncbi.nlm.nih.gov/pubmed/28630940 http://dx.doi.org/10.1128/mSphere.00205-17 |
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