Cargando…

Neurocardiovascular deficits in the Q175 mouse model of Huntington's disease

Cardiovascular dysautonomia as well as the deterioration of circadian rhythms are among the earliest detectable pathophysiological changes in individuals with Huntington's disease (HD). Preclinical research requires mouse models that recapitulate disease symptoms and the Q175 knock‐in model off...

Descripción completa

Detalles Bibliográficos
Autores principales: Cutler, Tamara S., Park, Saemi, Loh, Dawn H., Jordan, Maria C., Yokota, Tomohiro, Roos, Kenneth P., Ghiani, Cristina A., Colwell, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471434/
https://www.ncbi.nlm.nih.gov/pubmed/28576852
http://dx.doi.org/10.14814/phy2.13289