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Cytoresistance after acute kidney injury is limited to the recovery period of proximal tubule integrity and possibly involves Hippo‐YAP signaling

Rat proximal tubule (PT) cells that have recovered from severe acute kidney injury induced by uranyl acetate (UA) develop cytoresistance to subsequent UA treatments. We reported that enhanced G1 arrest might contribute to cytoresistance. Herein, we examined these mechanisms by investigating Yes‐asso...

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Detalles Bibliográficos
Autores principales: Iwakura, Takamasa, Fujigaki, Yoshihide, Fujikura, Tomoyuki, Tsuji, Takayuki, Ohashi, Naro, Kato, Akihiko, Yasuda, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471447/
https://www.ncbi.nlm.nih.gov/pubmed/28611154
http://dx.doi.org/10.14814/phy2.13310