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The Immunosignature of Mother/Fetus Couples in Gestational Diabetes Mellitus: Role of HLA-G 14 bp ins/del and PAPP-A A/C Polymorphisms in the Uterine Inflammatory Milieu

We enrolled 151 healthy mother/newborn couples and 26 with gestational diabetes mellitus (GDM). HLA-G and PAPP-A plasma levels were measured by ELISA at first and second trimesters, at delivery, and in cord blood. HLA-G 14 bp ins/del and PAPP-A A/C polymorphisms were genotyped. HLA-G del/del and PAP...

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Detalles Bibliográficos
Autores principales: Martinetti, Miryam, Beneventi, Fausta, Capittini, Cristina, Locatelli, Elena, Simonetta, Margherita, Cavagnoli, Chiara, De Maggio, Irene, De Silvestri, Annalisa, Pasi, Annamaria, Spinillo, Arsenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471558/
https://www.ncbi.nlm.nih.gov/pubmed/28655969
http://dx.doi.org/10.1155/2017/4254750