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Structural Probing and Molecular Modeling of the A(3) Adenosine Receptor: A Focus on Agonist Binding
Adenosine is an endogenous modulator exerting its functions through the activation of four adenosine receptor (AR) subtypes, termed A(1), A(2A), A(2B) and A(3), which belong to the G protein-coupled receptor (GPCR) superfamily. The human A(3)AR (hA(3)AR) subtype is implicated in several cytoprotecti...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471610/ https://www.ncbi.nlm.nih.gov/pubmed/28287473 http://dx.doi.org/10.3390/molecules22030449 |