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Interleukin-21 promotes thymopoiesis recovery following hematopoietic stem cell transplantation

BACKGROUND: Impaired T cell reconstitution remains a major deterrent in the field of bone marrow (BM) transplantation (BMT) due to pre-conditioning-induced damages inflicted to the thymi of recipient hosts. Given the previously reported thymo-stimulatory property of interleukin (IL)-21, we reasoned...

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Detalles Bibliográficos
Autores principales: Tormo, Aurélie, Khodayarian, Fatemeh, Cui, Yun, Al-Chami, Edouard, Kanjarawi, Reem, Noé, Beatriz, Wang, Huijie, Rafei, Moutih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471903/
https://www.ncbi.nlm.nih.gov/pubmed/28615039
http://dx.doi.org/10.1186/s13045-017-0490-3