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The role of cullin4B in human cancers

Cullin 4B (CUL4B) is a scaffold of the Cullin4B-Ring E3 ligase complex (CRL4B) that plays an important role in proteolysis and is implicated in tumorigenesis. Aberrant expression of CUL4B has been reported in various types of human diseases. Recently, studies have shown that CUL4B was overexpressed...

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Detalles Bibliográficos
Autores principales: Li, Ying, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471934/
https://www.ncbi.nlm.nih.gov/pubmed/28630798
http://dx.doi.org/10.1186/s40164-017-0077-2