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Identification of cancer-specific motifs in mimotope profiles of serum antibody repertoire

BACKGROUND: For fighting cancer, earlier detection is crucial. Circulating auto-antibodies produced by the patient’s own immune system after exposure to cancer proteins are promising bio-markers for the early detection of cancer. Since an antibody recognizes not the whole antigen but 4–7 critical am...

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Detalles Bibliográficos
Autores principales: Gerasimov, Ekaterina, Zelikovsky, Alex, Măndoiu, Ion, Ionov, Yurij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471937/
https://www.ncbi.nlm.nih.gov/pubmed/28617221
http://dx.doi.org/10.1186/s12859-017-1661-5