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Prediction models for drug-induced hepatotoxicity by using weighted molecular fingerprints
BACKGROUND: Drug-induced liver injury (DILI) is a critical issue in drug development because DILI causes failures in clinical trials and the withdrawal of approved drugs from the market. There have been many attempts to predict the risk of DILI based on in vivo and in silico identification of hepato...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471939/ https://www.ncbi.nlm.nih.gov/pubmed/28617228 http://dx.doi.org/10.1186/s12859-017-1638-4 |