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Chemokine receptor co-expression reveals aberrantly distributed T(H) effector memory cells in GPA patients
BACKGROUND: Persistent expansion of circulating CD4(+) effector memory T cells (T(EM)) in patients with granulomatosis with polyangiitis (GPA) suggests their fundamental role in disease pathogenesis. Recent studies have shown that distinct functional CD4(+) T(EM) cell subsets can be identified based...
Autores principales: | Lintermans, Lucas L., Rutgers, Abraham, Stegeman, Coen A., Heeringa, Peter, Abdulahad, Wayel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471953/ https://www.ncbi.nlm.nih.gov/pubmed/28615072 http://dx.doi.org/10.1186/s13075-017-1343-8 |
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