Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of γδ T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea

BACKGROUND: γδ T cells are important for both protective immunity and immunopathogenesis during malaria infection. However, the immunological processes determining beneficial or detrimental effects on disease outcome remain elusive. The aim of this study was to examine expression and regulatory effe...

Descripción completa

Detalles Bibliográficos
Autores principales: Schofield, Louis, Ioannidis, Lisa J., Karl, Stephan, Robinson, Leanne J., Tan, Qiao Y., Poole, Daniel P., Betuela, Inoni, Hill, Danika L., Siba, Peter M., Hansen, Diana S., Mueller, Ivo, Eriksson, Emily M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471992/
https://www.ncbi.nlm.nih.gov/pubmed/28615061
http://dx.doi.org/10.1186/s12916-017-0883-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471992/
https://www.ncbi.nlm.nih.gov/pubmed/28615061
http://dx.doi.org/10.1186/s12916-017-0883-8

Ejemplares similares