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SOX17 Regulates Conversion of Human Fibroblasts Into Endothelial Cells and Erythroblasts by Dedifferentiation Into CD34(+) Progenitor Cells

BACKGROUND: The mechanisms underlying the dedifferentiation and lineage conversion of adult human fibroblasts into functional endothelial cells have not yet been fully defined. Furthermore, it is not known whether fibroblast dedifferentiation recapitulates the generation of multipotent progenitors d...

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Detalles Bibliográficos
Autores principales: Zhang, Lianghui, Jambusaria, Ankit, Hong, Zhigang, Marsboom, Glenn, Toth, Peter T., Herbert, Brittney-Shea, Malik, Asrar B., Rehman, Jalees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472005/
https://www.ncbi.nlm.nih.gov/pubmed/28381471
http://dx.doi.org/10.1161/CIRCULATIONAHA.116.025722