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A novel application of the Staudinger ligation to access neutral cyclic di-nucleotide analog precursors via a divergent method
Our efforts to develop a scalable and divergent synthesis of cyclic di-nucleotide analog precursors have resulted in (1) an orthogonally protected di-amino carbohydrate as well as (2) the novel application of the Staudinger ligation to provide medium-sized macrocycles featuring carbamate or urea lin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472050/ https://www.ncbi.nlm.nih.gov/pubmed/28670448 http://dx.doi.org/10.1039/c7ra06045a |