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Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

Triple-negative breast cancer (TNBC) lacks effective treatment options due to the absence of traditional therapeutic targets. The epidermal growth factor receptor (EGFR) has emerged as a promising target for TNBC therapy because it is overexpressed in about 50% of TNBC patients. Here we describe a P...

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Detalles Bibliográficos
Autores principales: Su, Yu-Cheng, Burnouf, Pierre-Alain, Chuang, Kuo-Hsiang, Chen, Bing-Mae, Cheng, Tian-Lu, Roffler, Steve R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472176/
https://www.ncbi.nlm.nih.gov/pubmed/28593948
http://dx.doi.org/10.1038/ncomms15507